Identification and Functionality of Corona Virus using Genome Sequencing Analysis
Coronaviruses are enveloped RNA viruses prevalent in birds and mammals including humans causing severe respiratory, enteric, hepatic, and neurologic diseases.Given the high prevalence and wide distribution of coronaviruses, the large genetic diversity and frequent recombination of th
Project Title
Identification and Functionality of Corona Virus using Genome Sequencing Analysis
Project Area of Specialization
Project Summary
Coronaviruses are enveloped RNA viruses prevalent in birds and mammals including humans causing severe respiratory, enteric, hepatic, and neurologic diseases.Given the high prevalence and wide distribution of coronaviruses, the large genetic diversity and frequent recombination of their genomes, and increasing human–animal interface activities, novel coronaviruses are likely to emerge periodically in humans owing to frequent cross-species infections and occasional epiemics.
Therfore identification of specific drug targets to inhibit viral replicaiton is of tremendous importance to control its rapid spread.The project is designed to do a pilot study using differnt is-silico tools which aid in idntifiacion of novel drug targets.
Project Objectives
- To analyse genome of corona virus.
- To do similarity serach for the identification of evolutionary realtionship of corona virus.
- To discover putative drug targets of corona virus with reference to closely related species.
- Moleuclar Docking of discovered durg target with their potential inhibitors.
Project Implementation Method
Development of potential treatment option to control replication of corona virus.
Benefits of the Project
Identification of drug targets to control the spread of corona virus.
Technical Details of Final Deliverable
Software for molecualr docking GOLD license will be needed to get full technical support of software.
Final Deliverable of the Project
Core Industry
Other Industries
Core Technology
Other Technologies
Sustainable Development Goals
Required Resources
| Item Name | Type | No. of Units | Per Unit Cost (in Rs) | Total (in Rs) |
|---|---|---|---|---|
| Docking Software | Equipment | 1 | 70000 | 70000 |
| Data Collection | Miscellaneous | 1 | 10000 | 10000 |
| Total in (Rs) | 80000 |
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