Adil Khan 1 year ago
AdiKhanOfficial #FYP Ideas

Comparative study on Hydroxyapatite extraction from bovine and caprine bone

Statement of purpose Objectives: ? Extraction of hydroxyapatite from Bovine and Caprine bone. ? Characterization of hydroxyapatite by using XRD and FTIR. ? Comparison of results on the basis of molarity, temperature and time.

Project Title

Comparative study on Hydroxyapatite extraction from bovine and caprine bone

Project Area of Specialization

Shared Economy

Project Summary

Statement of purpose

Objectives:

Ø Extraction of hydroxyapatite from Bovine and Caprine bone.

Ø Characterization of hydroxyapatite by using XRD and FTIR.

Ø Comparison of results on the basis of molarity, temperature and time.

 Motivation:

The biomaterial is an emerging and challenging field in the healthcare sector. It has several applications in medicine such as prosthetics, orthopedics, dentistry, tissue engineering, and drug delivery system. We are fascinated to work in this field as our final year project. Working in the domain of biomaterials, we initiate our work based on “Comparative study on Hydroxyapatite extraction from Bovine and Caprine bone”. Hydroxyapatite has widely been used in various applications due to their excellent biocompatibility, bioactivity and osteoconduction characteristics. This material may be employed in many forms such as porous blocks, dense body, granular forms and hybrid composites for various biomedical applications..

Materials and devices required:

Materials

• Bones (Bovine and Caprine).

• Deionized water

• Sodium hydroxide

• Hydrogen peroxide

• Acetone

Machine and devices

• Automatic furnace

• Water bath

• Oven

• pH meter

Methodology

Ø Cleaning of raw bones.

Ø Chemical treatment of clean bones.

Ø Thermal treatment of samples.

Ø Characterization of the final product.

Result

The use of bones for the extraction of hydroxyapatite provide an environmentally beneficial and cost-effective medical grade biocompatible material. The characterization will confirm the purity and crystallinity of the final product.

Project Objectives

OBJECTIVES:

Ø Extraction of hydroxyapatite from Bovine and Caprine bone.

Ø Characterization of hydroxyapatite by using XRD and FTIR.

Ø Comparison of results on the basis of molarity, temperature and time.

Project Implementation Method

Starting from the collection of bones we boiled the bones with water to remove the muscular attachments and then cleaned the bones with a chemical solution(acetone & deionized water). then we divided bones into 10 samples and treat them with different concentration of chemicals. After chemical treatment, we calcinate the samples using the automatic furnace. In the last samples were grinded to reduce the particle size.

Benefits of the Project

  • Bone tissue engineering.
  • Coating of dental implants.
  • Re-mineralizing agent in toothpaste
  • Filtration of microorganisms.
  • In orthopaedics, fillers for bone voids
  • filler for maxillofacial and dental surgery
  • Repairing of periodontal disease and porous bone.
  • Drug and gene delivery.

Technical Details of Final Deliverable

Technical details of final deliverable:

Bones of cow and goat were collected as a raw material., beakers for holding the samples that were dipped in a chemical solution. Evaporated plates used for calcination.Motor and pestle for grinding the samples. Airtight bags used for storage of samples. FTIR, XRD & SEM test of samples for characterization.

Final Deliverable of the Project

Hardware System

Type of Industry

Manufacturing

Technologies

Shared Economy

Sustainable Development Goals

Responsible Consumption and Production

Required Resources

Item Name Type No. of Units Per Unit Cost (in Rs) Total (in Rs)
Caprine bones Miscellaneous 1050500
Bovine bones Miscellaneous 101001000
Beakers Miscellaneous 1040400
Evaporated plates Miscellaneous 1535525
airtight bags Miscellaneous 353105
Motor and pestle Miscellaneous 1500500
Stationary Miscellaneous 460240
Priting Miscellaneous 38301140
FTIR test Equipment203006000
XRD test Equipment2050010000
SEM test Equipment203006000
Transport(auto) Miscellaneous 91701530
Transport(karachi) Miscellaneous 25001000
Total in (Rs) 28940
If you need this project, please contact me on contact@adikhanofficial.com
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