bioluminous diseases detecting device

Project Title

bioluminous diseases detecting device

Project Area of Specialization Biomedical EngineeringProject Summary

Human life is suffering through many diseases that have to be detected but unfortunately, there are sufficient diseases for which we do not have any device to detect the diseases in a short period of time with accuracy. Evolution of this start from IMBEDs technology, which allows micro-chips to transmit the identification information to a reader through wireless communication by using IMBEDs reader, so we can identify any kind of disease using IMBEDs which mainly use heme-sensitive probiotic biosensor to detect such diseases and transmit it thought wireless. Microorganisms living on and in the human body constantly interrogate their biochemical surroundings and alter gene expression to adapt to changing environments. Synthetic biology enables the robust engineering of living cells with increasingly complex genetic circuits to sense biological inputs and control gene expression. Whole-cell biosensors harness this sensing ability to detect analytes associated with human health or environmental contamination. Owing to their innate robust functionality in complex physiological environments, biosensors have been developed to sense clinically relevant biomarkers in serum or urine ex vivo, as well as gut biomolecules supplemented in diet or generated during disease. However, despite their promise as noninvasive diagnostics, biosensors have yet to be employed for clinically compatible testing in an unobtrusive, real-time, and user-friendly way.

Project Objectives

Current technology focusing on the development of biologically-based detection systems has prompted efforts to address the need for methods for detecting specific diseases. Numerous methods for determining the presence of diseases have been used over the years; typically, culture methods were employed in the past but these methods were slow and inefficient. Recent developments in bio-reporter technology have prompted use of genetically engineered bacteria or bacteriophage to identify toxic chemical compounds and in some cases to identify particular species of bacteria.

Sayler et al. (1998) have described bioluminescent bacterial-based bioreporters that respond to specific compounds via the production of visible light. A variety of lux-based bacterial bioreporters has been used to detect and monitor naphthalene.

Project Implementation Method

To design a device that will detect specific diseases by using the ingestible bacterial-electronic system for such purpose Arduino will be used to operate the light-detecting sensors and to analyze the wavelength of the specific bio luminous light a wireless system will be connected to Arduino to obtain such results.

A cellular biosensor will be designed by the bio technician which will be used internally by the subject. The cellular biosensor will give an indication about the specific diseases in the subject. After the indication, the signal will be detected by (ingestible micro-bio-electronic device) IMBEDs device to display the results. Additionally, we integrate alternative biosensors to demonstrate the modularity and extensibility of the detection platform. IMBEDs enable new opportunities for biomarker discovery and could transform the management and diagnosis of disease.

Benefits of the Project

´These technological advances have the potential to make disease surveillance and treatment far more effective for a variety of conditions, allowing patients to lead longer and more productive lives.

´This prototype is the combination of energy, hardware, software, and communication system.

´These devices are used daily for fitness tracking and vital signs monitoring.

Technical Details of Final Deliverable

the ultra violet diseases detecting device is important in dignousing different kind of diseases in a short period of time living in 21 century it is essantail for us to save time and to detect disease with an easy way .

Final Deliverable of the Project HW/SW integrated systemCore Industry MedicalOther Industries Health , Telecommunication Core Technology Artificial Intelligence(AI)Other Technologies OthersSustainable Development Goals Good Health and Well-Being for PeopleRequired Resources

Item Name	Type	No. of Units	Per Unit Cost (in Rs)	Total (in Rs)
			Total in (Rs)	65000
Arduino pro	Equipment	2	1200	2400
sensors	Equipment	6	2000	12000
Different synthetic bacteria	Equipment	5	1000	5000
ultra low power battery	Equipment	1	8000	8000
connectivity device	Equipment	2	3800	7600
transport	Miscellaneous	4	2500	10000
structure designing	Equipment	1	20000	20000